Peptide Backbone Editing via Post-Translational O to C Acyl Shift (JACS, 2025)
C-GEM researchers developed a novel post-translational backbone editing reaction to replace a peptide bond with a C-C bond as diketones and heterocycles. This general strategy provides the first example of a C–C bond forming reaction to take place within the peptide backbone, as well as… Read More »Peptide Backbone Editing via Post-Translational O to C Acyl Shift (JACS, 2025)