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Structure of an archaeal ribosome reveals a divergent active site and hibernation factor (Nat Microbiol, 2025)

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By Amos Nissley C-GEM researchers identified archaeal ribosomes with highly divergent peptidyl transferase centers (PTC). Cryo-EM structures of the Pyrobaculum calidifontis ribosome revealed that unique archaeal ribosomal protein (rProtein) sequences reorganize the PTC, enabling rRNA sequence variation. Modifying E. coli rProteins to resemble those in… Read More »Structure of an archaeal ribosome reveals a divergent active site and hibernation factor (Nat Microbiol, 2025)

Recap: C-GEM Chats Careers with R1 Faculty

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C-GEM talked to Professor Jeffery Tharp and Professor Allison Walker about their experiences as faculty at research-intensive institutions. Professor Tharp is an Assistant Professor of Biochemistry and Molecular Biology at Indiana University, and Professor Walker is an Assistant Professor of Chemistry and Biological Sciences at… Read More »Recap: C-GEM Chats Careers with R1 Faculty

A woman in a laboratory setting conducting scientific research with test tubes.

C-GEM welcomes fifth cohort of summer undergraduates

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Welcome to the 2025 cohort of Summer Undergraduate Research Program (SURP) scholars! This year, we are hosting five scholars across UC Berkeley and Yale. Jacqueline Buenviaje (University of New Mexico) will be mentored by Dr. Alexandra Kent (postdoctoral scholar, Cate Lab). Adrienne Garcia (University of… Read More »C-GEM welcomes fifth cohort of summer undergraduates

C-GEM celebrates spring 2025 graduates

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Congratulations to the class of 2025! Leah Roe, Ph.D. (Schepartz Lab) and Kristina Boyko, Ph.D. (Cate Lab) received doctoral degrees, and Rebecca Bernstein (Cate Lab), Katie Fitzgerald (Cate Lab), Martina Boga de Teresa (Cate Lab), Cathy Zhu (Cate Lab), Arjun Garapaty (Schepartz Lab) received Bachelor’s… Read More »C-GEM celebrates spring 2025 graduates

C-GEM brings polymer science to Lawrence Hall of Science STEM Day

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On Saturday, C-GEM participated in STEM Day at the Lawrence Hall of Science (LHS). STEM Day celebrates innovative science education research performed at LHS and UC Berkeley. At STEM Day, C-GEM scientists demonstrated the science of biopolymers to over 800 museum guests using “Pasta-mers,” which… Read More »C-GEM brings polymer science to Lawrence Hall of Science STEM Day

C-GEM Celebrates NSF 75th Anniversary

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Saturday, May 10, 2025, marked the 75th anniversary of President Harry Truman signing into law the National Science Foundation (NSF) Act of 1950. It is hard to overstate the impact of 75 years of NSF-funded research. To celebrate the NSF’s 75th anniversary, members of C-GEM… Read More »C-GEM Celebrates NSF 75th Anniversary

Breakthrough Article: Monitoring monomer-specific acyl–tRNA levels in cells with PARTI (Nucleic Acids Res, 2025)

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C-GEM researchers developed a novel method called 3-Prime Adenosine-Retaining Aminoacyl–tRNA Isolation (PARTI), which determines precisely how much of a cellular tRNA is acylated, what it is acylated with, and whether it has been acylated once or twice. PARTI is an essential verification tool for optimizing… Read More »Breakthrough Article: Monitoring monomer-specific acyl–tRNA levels in cells with PARTI (Nucleic Acids Res, 2025)

Recap: C-GEM Chats Careers with Postdocs

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C-GEM talked to Dr. Paul Peterson and Dr. Carly Schissel about their experiences as postdoctoral scholars. Dr. Peterson is an NIH postdoctoral scholar in the Miller lab at Yale University, and Dr. Schissel is a Miller Institute Research Fellow in the Schepartz lab at UC… Read More »Recap: C-GEM Chats Careers with Postdocs

Dr. Carly Schissel accepts faculty position at Penn State

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Dr. Carly Schissel (Miller Fellow, Schepartz Lab) has accepted a position as an Assistant Professor of Chemistry at Penn State. She starts this Fall. Carly’s lab will focus on the design and discovery of bioactive and therapeutic peptides, taking advantage of molecular biology, synthetic chemistry,… Read More »Dr. Carly Schissel accepts faculty position at Penn State

Two C-GEM postdocs and Executive Director Smaga Present at ASBMB

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This week, Dr. Alexandra Kent (postdoctoral scholar, Cate lab), Dr. Chandrima Majumdar (postdoctoral scholar, Cate lab), and C-GEM Executive Director Dr. Sarah Smaga all attended the 2025 ASBMB Annual Meeting in Chicago. Alexandra and Chandrima both presented posters and were selected to speak in the… Read More »Two C-GEM postdocs and Executive Director Smaga Present at ASBMB

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