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New paper: Redirecting RiPP Biosynthetic Enzymes to Proteins and Backbone-Modified Substrates

Led by C-GEM postdoc Josh Walker, this paper describes the installation of thiazoline and thiazole backbone modifications in peptides and proteins, including those containing non-natural monomers. This work is a collaboration between the Schepartz and Francis labs, with contributions from Noah Hamlish, Avery Tytla, and Dan Brauer.

Read the paper: https://pubs.acs.org/doi/10.1021/acscentsci.1c01577

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